Gene description for KIF23 |
Gene name |
kinesin family member 23 |
Gene symbol |
KIF23 |
Other names/aliases |
CDA3 CDAIII CDAN3 CDAN3A CHO1 KNSL5 MKLP-1 MKLP1 |
Species |
Homo sapiens |
Experiment description of studies that identified KIF23 in Breast cancer cells |
1
|
Experiment ID | 575 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Breast cancer cells |
Sample name | BT549 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
2
|
Experiment ID | 578 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
3
|
Experiment ID | 1678 |
Identified molecule | Protein
|
Extracellular vesicle type | Exosomes |
MISEV | Small EVs |
Identification method | Mass spectrometry
|
PubMed ID |
34108659
|
Organism | Homo sapiens |
Experiment description | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker |
Authors | Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R. |
Journal name |
Nat Cell Biol
|
Publication year | 2021 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 - Exo-rich fractions 7-10 pooled |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry |
EV-TRACK |
-
|
|
|
4
|
Experiment ID | 1679 |
Identified molecule | Protein
|
Extracellular vesicle type | Exosomes |
MISEV | Small EVs |
Identification method | Mass spectrometry
|
PubMed ID |
34108659
|
Organism | Homo sapiens |
Experiment description | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker |
Authors | Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R. |
Journal name |
Nat Cell Biol
|
Publication year | 2021 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 - Exo-rich fractions 1-6 pooled |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
5
|
Experiment ID | 2867 |
Identified molecule | protein
|
Extracellular vesicle type | Small extracellular vesicles |
MISEV | Small EVs |
Identification method | Mass spectrometry
|
PubMed ID |
30918259
|
Organism | Homo sapiens |
Experiment description | Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A |
Authors | Im EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC. |
Journal name |
Nat Commun
|
Publication year | 2019 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry |
EV-TRACK |
-
|
|
|
6
|
Experiment ID | 2870 |
Identified molecule | protein
|
Extracellular vesicle type | Small extracellular vesicles |
MISEV | Small EVs |
Identification method | Mass spectrometry
|
PubMed ID |
30918259
|
Organism | Homo sapiens |
Experiment description | Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A |
Authors | Im EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC. |
Journal name |
Nat Commun
|
Publication year | 2019 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry |
EV-TRACK |
-
|
|
|
7
|
Experiment ID | 3350 |
Identified molecule | protein
|
Extracellular vesicle type | Supermeres |
MISEV | EV-like nanoparticles |
Identification method | Mass spectrometry
|
PubMed ID |
34887515
|
Organism | Homo sapiens |
Experiment description | Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets |
Authors | Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ. |
Journal name |
Nat Cell Biol
|
Publication year | 2021 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 |
Isolation/purification methods | Differential centrifugation Filtration Centrifugal ultrafiltration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry ELISA |
EV-TRACK |
-
|
|
|